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自然杀伤细胞(NK细胞)是体内细胞免疫功能的组成部份,在某些肿瘤和病原微生物感染中,起到免疫监视的作用。NK细胞能识别多种抗原,并有直接杀伤靶细胞的能力。因而NK细胞的杀伤作用与肿瘤的发生,发展,转移及预后均有直接关系。 阿片肽作为神经介质,它们是否参与调节NK细胞的杀伤功能,是近年来人们感兴趣的研究问题,有研究者提到亮氨酸脑啡呔(leucine enkephalin,LENK)和甲硫氨酸脑啡呔(methionine enkephalin,
Natural killer cells (NK cells) are components of cellular immune function in vivo, and play an immune surveillance role in certain tumor and pathogenic microorganism infections. NK cells recognize multiple antigens and have the ability to directly kill target cells. Therefore, the killing effect of NK cells has a direct relationship with the occurrence, development, metastasis and prognosis of tumors. Opioid peptides as neuronal mediators are involved in the regulation of the killing function of NK cells. They are of interest in recent years. Some researchers mention leucine enkephalin (LENK) and methionine-enkephalin.呔(methionine enkephalin,