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本文报告1962年夏我所因液体误配,致使12例腹泻脱水患儿输液后发生高钠血症。我们进行了系统观察,并在1例作了水、电解质代谢平衡试验。误配液体含钠210 mEq/L,钠实际总入量为16.5至32.5 mEq/L,代谢平衡试验病例总体液、细胞外液量增加,细胞内液减少,反映有钠潴留及细胞内脱水。当时不知钠浓度,又无电解质测定结果,医生根据临床高钠症状,及时用葡萄糖液稀释瓶内液体,使输入液含钠童有所降低,并进行对症处理,全部痊愈出院。1～11月后随诊8例,无异常;22年后(1984年)追查到4例智力发育良好,无后遗症。我们认为临床症状对诊断高钠血症很有帮助。
This article reports the summer of 1962, due to mis-allocation of liquid, resulting in 12 cases of children with diarrhea and dehydration hypernatremia after infusion. We conducted a systematic observation, and in 1 case made a balance of water and electrolyte metabolism. Mismatched liquid sodium 210 mEq / L, the actual total amount of sodium 16.5 to 32.5 mEq / L, metabolic balance test cases of total fluid, extracellular fluid volume increased, decreased intracellular fluid, reflecting sodium retention and intracellular dehydration. At that time I do not know the sodium concentration, and no electrolyte test results, the doctor according to clinical symptoms of high sodium, diluted with glucose solution in a timely manner the bottle of liquid, the sodium infusion of sodium decreased, and symptomatic treatment, all discharged. From January to November, 8 cases were followed up, no abnormality was found. After 22 years (1984), 4 cases of good mental development were found without sequelae. We think clinical symptoms are helpful for the diagnosis of hypernatremia.