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１引言 阿仑膦酸钠为二膦酸盐类药物，广泛用于治疗骨质疏松症。目前该药多采用钼蓝比色法测定含量。但“钼蓝比色法”的测定波长及结果易受还原剂种类、性质及溶液酸度等因素的影响，而且操作繁琐。鉴于阿仑膦酸钠经氧化破坏可定量生成ＰＯ４３－，且ＰＯ４３－又能与饥铝酸盐
1 Introduction alendronate is a bisphosphonates, widely used in the treatment of osteoporosis. At present, the drug used molybdenum blue colorimetric assay. However, “Molybdenum Blue Colorimetric” determination of the wavelength and the results vulnerable to the type of reducing agent, nature and solution acidity and other factors, and the operation cumbersome. In view of alendronate oxidative damage can be generated quantitative PO43-, and PO43-and can be hung with the aluminate