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小儿肺炎为儿科最常见的疾病,尤其是冬春季,发病率、死亡率高。寻找理想的治疗方案,提高治愈率、降低死亡率是儿科医生一直探索的课题。我们对120例重症肺炎采用大剂量干扰素治疗,结果治疗组比对照组发烧时间明显缩短(P<0.01),心衰纠正迅速(P<0.01),肺部X线显示炎症影吸收快(P<0.05),总的治愈率为(80％),死亡率明显低(2.5％),病程明显缩短(P<0.01)等优点。我们认为大剂量干扰素不仅有很强的抗病毒作用而且具有提高机体免疫功能的作用,值得临床广泛应用。
Pediatric pneumonia is the most common pediatric disease, especially in winter and spring, morbidity and mortality are high. Looking for the ideal treatment plan to improve the cure rate and reduce the mortality rate is the subject of constant exploration by pediatricians. We treated 120 patients with severe pneumonia with high-dose interferon. The results showed that the treatment group had a significantly shorter duration of fever (P <0.01), faster heart failure correction (P <0.01), and pulmonary X-ray showed faster absorption of inflammation <0.05). The overall cure rate was (80%), the mortality rate was significantly lower (2.5%), and the course of disease significantly shorter (P <0.01). We believe that high-dose interferon not only has a strong antiviral effect but also has the function of improving the body’s immune function, which deserves to be widely used clinically.