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目的:评价房间隔缺损(ASD)介入治疗的临床疗效。方法:全组1000例,男421例,女579例,年龄1.2～76(23±4)岁,经临床、心电图、X线及经胸超声心动图(TTE)检查诊断为ASD继发孔型,TTE测不同切面ASD的最大直径6～34(19±4)mm,其中单孔ASD为970例,多孔ASD30例。结果:1000例均1次封堵成功,技术成功率99%,所用封堵器直径为10～40(22±6)mm,30例多孔ASD,有26例置入1个封堵器直接封堵2个缺损孔,4例分别用2个封堵器加以封堵2个缺损孔。结论:ASD的介入治疗具有操作简便易行、无创伤、风险小、安全可靠、技术成功率高、住院时间短等优点,深受患者及临床医生的欢迎,已成为当今治疗ASD的首选方法。
Objective: To evaluate the clinical effect of atrial septal defect (ASD) interventional therapy. Methods: A total of 1000 patients were enrolled, including 421 males and 579 females aged from 1.2 to 76 years (23 ± 4 years). All the patients were diagnosed as secondary ASD by clinical, electrocardiogram, X-ray and transthoracic echocardiography (TTE) The maximum diameter of ASD was 6 ~ 34 (19 ± 4) mm in different section of TTE, including 970 cases of single-hole ASD and 30 cases of porous ASD. Results: All of the 1000 cases were successfully occluded once, with a technical success rate of 99%. The diameter of the occluder used was 10 ~ 40 (22 ± 6) mm, 30 cases of porous ASD, and 26 cases were implanted with an occluder direct seal Two defect holes were blocked, and two defect holes were blocked in 4 cases with two occluders respectively. Conclusion: The interventional therapy of ASD has the advantages of easy operation, no trauma, low risk, safe and reliable, high technical success rate and short hospital stay. It has been welcomed by patients and clinicians and has become the preferred method of treatment for ASD.