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目的 提高脉络丛乳头状瘤的CT和MRI诊断水平。方法 进行 18例CT和MRI检查与手术病理 -光镜、电镜超微结构和免疫组化对照研究。结果 肿瘤位于脑室系统 14例 ,小脑 4例。CT表现为略高密度或混合密度肿瘤伴钙化 ;MRIT1WI呈低信号或混合信号 ,T2WI呈高信号。光镜和电镜 :显示肿瘤细胞单层或复层排列 ,有胶原纤维、毛细血管、钙化小体等。免疫组化 :vimentin、S 10 0、cytokeratin、EMA、GFAP均表达阳性。对照组室管膜瘤则cytokeratin和EMA表达阴性。结论 提高CT、MRI对脉络丛乳头状瘤与室管膜瘤的鉴别诊断水平 ,有益于治疗
Objective To improve CT and MRI diagnosis of choroid plexus papilloma. Methods 18 cases of CT and MRI examinations were compared with surgical pathology-ultrasound and electron microscopy ultrastructure and immunohistochemistry. Results The tumor located in the ventricle system in 14 cases and the cerebellum in 4 cases. CT showed a slightly higher density or mixed density tumor with calcification; MRIT1WI showed low signal or mixed signal, T2WI showed high signal. Light and electron microscopy: Single or multiple layers of tumor cells, collagen fibers, capillaries, and calcified bodies. Immunohistochemistry: positive expression of vimentin, S 10 0, cytokeratin, EMA, and GFAP. In the control group, chemokine tumors showed negative cytokeratin and EMA expression. Conclusion To improve the differential diagnosis of choroid plexus papilloma and ependymoma by CT and MRI is beneficial to the treatment