芯片毛细管电泳 (Chip CE)技术在近几年已取得了很大的进展。本文着重介绍芯片毛细管区带电泳技术 ,对等电聚焦、等速电泳、自由溶液电泳及胶束电动色谱等其它芯片电泳模式也有所提及。讨论了芯片材料和制作技术、芯片的几何形状、样品的操作和衍生、检测及芯片毛细管电泳技术的应用 ,特别是在核酸和蛋白质的分离分析中的进展 Chip CE has made great strides in recent years. This article focuses on the chip capillary zone electrophoresis technique, and other chip electrophoresis modes such as isoelectric focusing, isokinetic electrophoresis, free-radical electrophoresis and micellar electrokinetics are also mentioned. Discusses chip material and fabrication techniques, chip geometry, sample manipulation and derivatization, detection, and chip capillary electrophoresis, especially in nucleic acid and protein separations