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对78例偏头痛患者和21例正常健康人对照的血清镁离子的测定，结果发现偏头痛患者发作期血清镁水平为0．82±0．12mmol／L，自然缓解期为0．87±0．12mmol／L，均显著低于正常对照组的0．95±0．14mmol／L（P＜0．01和0．05）；而补镁治疗后缓解或血清镁水平为0．94±0．15mmol／L，显著高于发作期和自然缓解期（P＜0．01和0．05），与正常对照组无差异（P＞0．05）。认为血清镁在偏头痛的发病中起重要作用，以及在发作期补充镁离子可起到良好的治疗和预防作用。
The determination of serum magnesium in 78 migraineurs and 21 healthy controls showed that serum magnesium levels in migraineurs were 0.82 ± 0.12 mmol / L and those in spontaneous remission were 0.87 ± 0 .12mmol / L, all of which were significantly lower than those of the normal control group (0.95 ± 0.14mmol / L, P <0.01 and 0.05) .15mmol / L, significantly higher than the onset and natural remission (P <0.01 and 0.05), no difference with the normal control group (P> 0.05). Serum magnesium is thought to play an important role in the pathogenesis of migraine and to supplement and supplement magnesium ions during the attack to provide a good therapeutic and prophylactic effect.