凝血研究不再限于血液学家了,在不久前举行的一次“凝血、癌症和炎症”会议上,会议主席Edgington指出,凝血过程不只是血栓研究者的地盘,而且也是病人重要的应答系统。目前认为,凝血不仅为防止外伤性出血所必需,而且凝血的激活似乎还是机体免疫反应的一部分。凝血异常对血管疾病(包括冠心病)的影响早已为人所知,而新近的研究表明,凝血过程也累及变态反应和炎症状态。此外,血凝块在癌细胞周围沉积也会有助于恶性肿瘤的繁衍。最近3～4年来细胞对凝血系统和纤溶系统活化所起的作用日渐为人了解。包括巨噬细胞 Coagulation research is no longer limited to hematologists. At a meeting called “Coagulation, Cancer, and Inflammation,” held not long ago, Edgington, chairman of the conference, pointed out that the clotting process is not only the site of thrombus researchers, but also an important patient response system. It is currently believed that coagulation is not only necessary to prevent traumatic bleeding, but that activation of coagulation appears to be part of the body’s immune response. The effects of abnormal blood coagulation on vascular diseases (including coronary heart disease) have long been known, and recent studies have shown that the blood coagulation process also involves allergic and inflammatory conditions. In addition, the deposition of blood clots around the cancer cells can also contribute to the proliferation of malignant tumors. The role of cells in the activation of the coagulation system and the fibrinolysis system in the last 3 to 4 years is increasingly understood. Including macrophages