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目的研究废旧变压器拆解点周围妇女儿童多氯联苯(PCBs)暴露水平及危险性评价。方法以F地区为研究现场,选择该地区中心小学50名8~10岁学龄儿童和其母亲为研究对象,采集妇女儿童空腹外周静脉血,用Agilent 5973N GC-MSD超痕量分析方法检测其PCBs(13个异构体)含量及血液、尿液临床生化检验,并作调查问卷及健康体检,最后作危险度评价。结果妇女和儿童外周静脉血中多氯联苯几何均值分别达175.9 ng/g、191.6 ng/g类脂;健康体检,儿童龋齿率82%。结论该地区妇女儿童血液中的PCBs含量已经有一定的蓄积水平,并且二者有较好的线性关系(r=0.736 3)。危险度评价提示,妇女PCBs内暴露已处于临界水平,5名母亲血液中PCBs的水平超过了5μg/g。根据加拿大咨询专家D r.Andy G ilm en提供的PCBs指南标准,已有10%的妇女应该受到关注。
Objective To study the exposure levels and risk assessment of PCBs in women and children around the dismantling point of waste transformer. Methods A total of 50 schoolchildren aged 8-10 years old and their mothers were selected as study sites in F district. Fasting peripheral venous blood was collected from women and children, and their PCBs were detected by the Agilent 5973N GC-MSD ultra-trace analysis (13 isomers) content and blood, urine clinical and biochemical tests, and questionnaires and health examination, and finally for the risk assessment. Results The geometric mean of polychlorinated biphenyls in peripheral venous blood of women and children reached 175.9 ng / g and 191.6 ng / g respectively. The health examination and the rate of dental caries in children were 82%. Conclusion The blood levels of PCBs in women and children in this area have reached a certain level of accumulation, and there is a good linear relationship between them (r = 0.736 3). The risk assessment suggests that exposure of women within PCBs is at a critical level and that levels of PCBs in the blood of five mothers exceed 5 μg / g. According to the guidelines for PCBs guidelines provided by Canadian consultant Dr. Dy Gillman, 10% of women should be concerned.