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目的:探讨半夏泻心汤联合质子泵抑制剂埃索美拉唑镁肠溶片治疗胃食管反流病的临床疗效。方法:2015年10月至2016年10月期间,我院收治胃食管反流病患者80例,随机分为两组,各40例。一组采用半夏泻心汤联合埃索美拉唑镁肠溶片治疗,另一组单纯采用埃索美拉唑镁肠溶片治疗。治疗6-8周后观察两组患者的治疗情况。结果:联合治疗组痊愈患者占75.00%,显效患者占12.50%,好转患者占7.50%,无效患者仅占5.00%,而单纯治疗组患者分别为32.50%、25.00%、122.50%和20.00%,秩和检验差异有统计学意义(P<0.05)。治疗有效率的比较,联合治疗组有效率为95.00%,单纯治疗组为80.00%,比较差异有统计学意义(P<0.05)。结论:中药方剂半夏泻心汤联合埃索美拉唑镁肠溶片治疗胃食管反流病临床效果较好,治愈率高,临床上值得推广应用。
Objective: To investigate the clinical efficacy of Banxiaxiexin Decoction combined with proton pump inhibitor esomeprazole magnesium enteric-coated tablet in the treatment of gastroesophageal reflux disease. Methods: From October 2015 to October 2016, 80 cases of gastroesophageal reflux disease in our hospital were randomly divided into two groups of 40 cases each. One group treated with Banxiaxiexin Decoction combined with esomeprazole magnesium enteric-coated tablets, while the other group treated with Esomeprazole-only enteric-coated tablets. After 6-8 weeks of treatment, the treatment of both groups was observed. Results: In the combination therapy group, 75.00% were cured, 12.50% were markedly effective, 7.50% were improved, 5.00% were ineffective, and were 32.50%, 25.00%, 122.50% and 20.00% respectively in the treatment group And test difference was statistically significant (P <0.05). The effective rate was 95.00% in the combined treatment group and 80.00% in the simple treatment group, the difference was statistically significant (P <0.05). Conclusion: The traditional Chinese medicine Banxiaxiexin Decoction combined with esomeprazole magnesium enteric-coated tablets in the treatment of gastroesophageal reflux disease clinical effect is better, the cure rate is high, it is worth to promote the clinical application.