镁的致泻、抗酸、利胆、抑制中枢神经以及其缺乏症、代谢紊乱等方面的资料和报道已很多。近年来,对镁的生理、药理作用及临床应用的研究,又有了不少进展。本文仅就镁的药理与临床研究作一简要综述。一、镁与心脏病镁对心脏病有一定疗效在50年代就有报道。1957年,开始报道在软水地区冠心病的发病率高于硬水地区。其后,证明了这与软水中镁含量较低有关,饮用含镁较多的硬水对预防心血管病有利。 Seeling认为,激素、射血阻抗、缺血、年龄、营养等引起心脏病的因素,均可引起心肌镁 Magnesium diarrhea, acid, gallbladder, central nervous system and its lack of inhibition, metabolic disorders and other aspects of the information and reports have a lot. In recent years, the physiological, pharmacological effects of magnesium and clinical application of research, there have been a lot of progress. This article only a brief overview of magnesium pharmacology and clinical research. First, magnesium and heart disease Magnesium has a certain effect on heart disease in the 50’s have been reported. In 1957, it was reported that the incidence of coronary heart disease was higher in soft water areas than in hard water areas. Later on, it was proved that this is related to the lower magnesium content in soft water and drinking hard water containing more magnesium is good for prevention of cardiovascular diseases. Seeling that hormones, ejection resistance, ischemia, age, nutrition and other factors that cause heart disease, can cause myocardial magnesium