观察了32例重症肺心病 ADP 诱导的血小板聚集功能(简称 PA)和血液流变学,并和所测正常人、高血压病、冠心病、脑梗塞进行对比。结果:PA 测定值以肺心组最高,与正常人和其他组相比均有显著性差异(P<0.01);肺心组全血粘度和血球压积升高亦显著高于正常人和冠心组(P<0.01)。提示 PA 升高可促进高凝状态,DIC、微血栓形成和肺动脉高压。使用川芎嗪、丹参、肝素、心痛定等抗 PA 和抗凝药物,降低了病死率。 The ADP-induced platelet aggregation (PA) and hemorheology in 32 patients with severe pulmonary heart disease were observed and compared with those measured in normal subjects, hypertensive patients, coronary heart disease and cerebral infarction. Results: The measured values ​​of PA were the highest in the group of pulmonary heart and the difference was significant (P <0.01) compared with the normal group and other groups. The increase of whole blood viscosity and hematocrit in the pulmonary heart group were also significantly higher than those in the normal and coronal groups Heart group (P <0.01). Prompted PA increased can promote hypercoagulable state, DIC, micro thrombosis and pulmonary hypertension. The use of ligustrazine, Salvia, heparin, nifedipine and other anti-PA and anticoagulant drugs, reducing mortality.