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目的:探讨吉林省尿路结石病人结石成分与血清元素的关系及其发生机制。方法:用原子吸收光谱分析法和自动生化分析仪测定血清和结石中元素的含量。结果:同一种尿路结石可有3￣5种不同组分,以草酸钙、磷酸钙和尿酸钙为主,结石中含有Ca、Zn、Fe、Mg、Mn、Cu、Pb、Na、K、Al、Sr、Cd等元素,其中Ca++、Na+、Fe++元素含量较高,尿路结石病人血清中Ca++、Na+、Fe++含量[(4.10±1.16)mmol/L、(156±7.8)mmol/L、(19.46±3.83)mmol/L]明显高于正常人[(2.30±0.05)mmol/L、(140±5.0)mmol/L、(16.37±2.26)mmol/L],其与结石中上述元素含量呈正相关。结论:钙代谢异常是尿路结石形成的重要原因之一。
Objective: To investigate the relationship between stone components and serum elements in urolithiasis and its mechanism in Jilin Province. Methods: The contents of elements in serum and calculus were determined by atomic absorption spectrometry and automatic biochemical analyzer. Results: The same type of urinary tract stones can have 3 to 5 different components, mainly calcium oxalate, calcium phosphate and calcium sulfate, stones containing Ca, Zn, Fe, Mg, Mn, Cu, Pb, Na, K, Al, Sr, Cd and other elements, of which Ca ++, Na + and Fe ++ were higher in the patients with urolithiasis (4.10 ± 1.16 mmol / L, 156 ± 7.8 mmol / L, (19.46 ± 3.83) mmol / L] were significantly higher than those in normal controls [(2.30 ± 0.05) mmol / L, (140 ± 5.0) mmol / L, Was positively correlated. Conclusion: Calcium metabolism is one of the important causes of urolithiasis.