良性前列腺增生(BPH)在中老年人中较为高发,严重时其相关症状明显又严重影响其生活质量。而治疗上目前多选用药物治疗,其中坦索罗辛为最常用药之一。然而既往关于坦索罗辛治疗中老年人BPH与其继发性严重低血压风险间关系尚不清楚,现就此进行大样本调查分析。受试对象为383 567例罹患BPH的中老年人,基线年龄40~85岁。并在先期除外接受过手术治疗、微波治疗、急性尿潴留等者,同时排除使用可能引起低血压的诸药者后纳入研究。研究中分为初始1~4周、5~8周和9~12周服用坦索罗辛,后再撤 Benign prostatic hyperplasia (BPH) in the elderly are more frequent, serious symptoms related to their significantly and seriously affect their quality of life. The treatment of the current selection of multiple drug treatment, including tamsulosin as one of the most commonly used drugs. However, previous studies on the relationship between tamsulosin and BPH in middle-aged and elderly patients with the risk of secondary hypotension are still unclear. Therefore, a large sample survey and analysis was conducted. Subjects were 383 567 middle-aged and elderly people with BPH, with a baseline age of 40-85 years. And in addition to prior surgery, microwave treatment, acute urinary retention, etc., while excluding the use of drugs that may cause hypotension after the inclusion of the study. The study was divided into the initial 1 to 4 weeks, 5 to 8 weeks and 9 to 12 weeks tamsulosin, and then withdraw