作为分泌性中耳炎病理学特征的中耳渗液是滞留于中耳腔的炎性液体之一。血浆渗漏到炎性液体中的血管舒缩素前体,通过Ⅻa因子和其它蛋白酶的作用很快变成血管舒缩素。来源于高分子量、随后形成血管舒缩素的缓激肽是一种比组织胺更为有力的化学介质,它可提高炎性组织的血管通透性,导致大量血浆渗漏。本文作者通过荧光法对27名成年人的30份中耳渗液标本进行了检测,来观察中耳渗液中血管舒缩素前体含量,以估价中耳渗液的血浆渗漏程度。所取样本均在无菌条件下经鼓膜抽吸,其中25份浆液性渗液,5份粘液样渗液。结果如下:浆液性渗液组血管舒缩素前体含量显著高于粘液样渗液组,这是由于后者中的血管舒缩素激肽系统已大部被消耗掉。而在浆液性渗液中,有9 Middle ear effusion, which is a pathological feature of secretory otitis media, is one of the inflammatory fluids that persist in the middle ear cavity. The precursor of the vasomotor plasma that leaks into the inflammatory fluid in plasma rapidly becomes the vasomotor by the action of factor κa and other proteases. Bradykinin, which is derived from high molecular weight, and then forms thrombin, is a more potent chemical mediator than histamine which increases vascular permeability of inflammatory tissues resulting in extensive plasma leakage. The authors examined 30 middle ear effusion specimens of 27 adults by fluorimetry to observe the content of the prostanoids in the middle ear effusion to assess the plasma leakage of the middle ear effusion. The samples were aseptic conditions by the tympanic membrane suction, of which 25 serous exudate, 5 mucus-like exudate. The results were as follows: The serous effusion group had a significantly higher pre-volume of the prosthetic than the mucus-like exudate group due to the fact that the latter has been largely consumed by the vasomotor kinin system. In serous exudate, there are 9