论文部分内容阅读
目的观察负压封闭引流技术(VSD)对慢性创面修复的疗效。方法选取慢性创面患者62例,随机均分为VSD组及对照组。两组均予以抗感染,改善微循环治疗;VSD组早期应用VSD处理创面,对照组用凡士林及聚维酮纱布外敷。两组均在创面肉芽生长满意后再行后续治疗。比较两组二期创面闭合时间、住院时间、抗生素费用及不同时间点创缘毛细血管密度、血小板衍生因子(PDGF)水平。结果 VSD组二期创面闭合时间、住院时间及抗生素费用少于对照组(P<0.01)。治疗后VSD组毛细血管密度及PDGF水平在不同时间点均高于对照组(P<0.05)。结论 VSD对慢性创面的修复优于传统方法,其机制可能与促进毛细血管及组织细胞生成有关。
Objective To observe the curative effect of negative pressure closed drainage (VSD) on chronic wound repair. Methods Totally 62 patients with chronic wounds were randomly divided into VSD group and control group. The two groups were given anti-infection, improve microcirculation treatment; VSD group treated with VSD early wounds, the control group with Vaseline and povidone gauze topical. Both groups were satisfied with the growth of wound granulation after follow-up treatment. The wound closure time, hospital stay, antibiotic expense and wounding capillary density and platelet-derived factor (PDGF) at two time points were compared between the two groups. Results The closure time, hospitalization time and antibiotic cost of the second wound in VSD group were less than those in the control group (P <0.01). After treatment, the capillary density and PDGF level in VSD group were higher than those in control group at different time points (P <0.05). Conclusion VSD is superior to traditional methods in repairing chronic wounds, and its mechanism may be related to the promotion of capillary and tissue cell generation.