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患者、女、56岁.因高血压病史20年.人院治疗.入院时BP23/12kPa,P72次/min.心电图正常.5d后血压29/13kPa,P78次/min,开始服比索洛尔(康可,德国默克药厂生产,深圳协和医药实业公司提供)5mg.bid.次日BP20/12kPa.P68次/min.于眼药第1O天出现胸闷不适.心电图示“高度窦房传导阻滞”,即停服比索洛尔、予心电监护,次日高度窦房传导阻滞消失.窦性心律64次/min.3d后再予比索洛尔5mg口服,11h后再次出现“窦性心动过缓、窦良传导阻滞”,即停用比索洛尔,井口服舒喘灵.次日转为正常窦性心律.66次/min,继续心电监护,未再出现窦缓及窦房传导阻滞.3d后行食道心房调搏示:窦房传导时间及窦房结功能恢复时间均正常,遂改服尼卡地平治疗.
Patients, female, 56 years old .Hypertension due to a history of 20 years .Hospital treatment.Admission BP23 / 12kPa, P72 times / min.Electrocardiogram normal .5d after the blood pressure 29 / 13kPa, P78 times / min, began taking bisoprolol Kang Ke, Germany Merck pharmaceutical production, Shenzhen Pharmaceutical Co., Ltd. Concord) 5mg.bid. The next day BP20 / 12kPa.P68 times / min. In ophthalmic 1O days appear chest tightness. ECG shows “a high degree of sinoatrial resistance Hysterectomy, bisoprolol was stopped and electrocardiogram monitoring was performed, the next day a high degree of sinoatrial block disappeared Sinus rhythm 64 times / min.3d and then to bisoprolol 5mg orally, again after 11h ”sinus Bradycardia, sinus Liang conduction block ", that disable the bisoprolol, well oral salbutamol. The next day to normal sinus rhythm .66 beats / min, ECG monitoring continued, there is no recurrence of sinus and sinus Room conduction block.3d after esophageal atrial pacing showed: sinoatrial conduction time and sinus node function recovery time are normal, then change to service nicardipine treatment.