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Prabhakaran等氏首次做了有关麻风杆菌和裸鼠的报告。他们报告与普通鼠比较麻风杆菌在裸鼠中的繁殖没有增加,也没有感染播散的证据。但是,这一结论所基于接种后的观察时间只有6个月,这样太短的时间间隙是无法发现细菌的显著增长的。1976年我们和Colston与Hilson二氏分别报告了裸鼠对麻风杆菌感染非常敏感这一事实。
For the first time, Prabhakaran et al. Reported on leprosy and nude mice. They reported no increase in the multiplication of leprosy in nude mice compared with that of normal rats and no evidence of spread of infection. However, this conclusion is based on the observation time after inoculation is only 6 months, so too short a time gap is not able to find a significant increase in bacteria. In 1976 we and Colston and Hilson two respectively reported the fact that nude mice were very sensitive to leprosy infections.