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用特异性ＤＮＡ 片断标记法（ＴＵＮＥＬ） 研究了２５例皮肤鳞状细胞癌（ＳＣＣ） ，同时观察了Ｂａｘ 和Ｂｃｌ２ 基因的表达。结果１９ 例发现凋亡细胞，６ 例Ｂｃｌ２ 弱阳性染色， 全部病例Ｂａｘ 染色阳性， 调亡均数与Ｂａｘ 强度显著正相关，推测ＳＣＣ 发生的原因不是由于细胞凋亡受到抑制。
Twenty-five cases of cutaneous squamous cell carcinoma (SCC) were studied using specific DNA fragment labeling (TUNEL). The expression of Bax and Bcl-2 genes was also observed. Results Apoptotic cells were found in 19 cases, and 6 cases were weakly stained with Bcl-2. All cases were positive for Bax staining, and the mean number of apoptosis was positively correlated with Bax intensity. It was speculated that the cause of SCC was not due to inhibition of apoptosis.