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本文选用动态血压监测（ABPM）的平均动脉压（MBP）与血压负荷（Load）参数作为对高血压病靶器官损伤（TOD）的评价指标。通过对63例正常血压与31例高血压病Ⅰ期，93例高血压病Ⅱ期和45例高血压病Ⅲ期患者进行动态血压监测。结果显示24小时平均动脉压（24h－MBP）在高血压各期组中均增高。在正常组、Ⅰ期组和Ⅱ期组之间均有非常显著的差异（P＜0．001）；但在Ⅱ期组与Ⅲ期组间无显著性差异（P＞0．05）。24小时血压负荷（24h－PL）和白昼血压负荷（d－PL）在正常组、Ⅰ期组与Ⅱ期组之间也有非常显著的差异（P＜0．001），但在Ⅱ期组与Ⅲ期组间无显著性差异（P＞0．05）。夜间血压负荷（n－PL）在Ⅰ期组、Ⅱ期组和Ⅲ期组之间均有非常显著的差异（P＜0．001）。因此，靶器官损伤与否及其程度，夜间血压负荷值有更高的评价意义。
In this paper, mean arterial pressure (MBP) and blood pressure (Load) parameters of ambulatory blood pressure monitoring (ABPM) were selected to evaluate target organ damage (TOD) in hypertensive patients. Ambulatory blood pressure monitoring was performed on 63 patients with normotensive blood pressure and 31 patients with stage Ⅰ hypertension, 93 patients with stage Ⅱ hypertension and 45 patients with stage Ⅲ hypertension. The results showed that 24-hour mean arterial pressure (24h-MBP) increased in all stages of hypertension. In the normal group, there was a significant difference between group Ⅰ and group Ⅱ (P <0.001), but there was no significant difference between group Ⅱ and group Ⅲ (P0.05). There was also a significant difference (P <0.001) between the 24-hour blood pressure load (24h-PL) and day blood pressure load (d-PL) in the normal group, There was no significant difference between the three groups (P> 0.05). Night nocturnal blood pressure (n-PL) was significantly different between stage I, stage II, and stage III (P <0.001). Therefore, the target organ damage or not and its extent, night blood pressure load value has a higher evaluation.