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目的探讨慢性肾脏病(CKD)患儿激素药服用依从性及其影响因素,寻求相应的护理对策。方法 2013年5月-12月对96例CKD患儿在出院期间激素药服用状况进行调查,并对影响因素进行分析。结果激素药服用不依从者50例,占52%。主要监护人、父亲文化程度、母亲文化程度、居住地、病程、住院次数、治疗方案认知情况不同的患儿服药依从性间差异有统计学意义(P<0.05)。多因素logistic回归分析表明患儿病程[OR=2.204,95%CI(1.253,3.875),P=0.006]、居住地[OR=2.615,95%CI(1.023,6.687),P=0.045]、母亲文化程度[OR=0.147,95%CI(0.028,0.788),P=0.025]为影响患儿服药依从性的独立因素。结论 CKD患儿激素药服用依从性现状不容乐观,应积极采取有针对性的护理干预,提高患儿激素服药依从性,从而达到有效控制疾病和延缓疾病进展的目的。
Objective To investigate the compliance of hormone drugs and its influencing factors in children with chronic kidney disease (CKD) and seek corresponding nursing measures. Methods From May 2013 to December 2013, 96 children with CKD were investigated for taking hormone drugs during discharge and the influencing factors were analyzed. Results 50 cases of hormone medication do not comply, accounting for 52%. There was significant difference (P <0.05) in medication compliance among the main guardians, father’s education level, mother’s education, residence, course of disease, number of hospitalizations and cognition of treatment regimens. Multivariate logistic regression analysis showed that the duration of illness [OR = 2.204, 95% CI (1.253, 3.875), P = 0.006], place of residence [OR = 2.615,95% CI 1.023,6.687, P = 0.045] The educational level [OR = 0.147, 95% CI (0.028,0.788), P = 0.025] was an independent factor affecting the medication compliance in children. Conclusions The status of compliance of hormone drugs in children with CKD is not optimistic. It is necessary to take targeted nursing interventions and improve the compliance of hormone medication in children so as to effectively control the disease and delay the progression of the disease.