药物过敏反应是由于应用某些药物所引起的一种反应,不论注射、口服或直接接触都可能发生。它不同于药物的副作用和中毒,它与该药的药理作用无关,因此往往是不能预知的。近年来,药物过敏反应的发病率不断增加,认识和正确处理这个问题是很重要的。药物过敏反应的机制,一般都认为是基于抗原与抗体结合所发生的变态反应,有人称之为药物变态反应。此时,药物常被认为是一种半抗原,进入机体后药物或其代谢产物与血液或组织中某种蛋白质结合,刺激机体产生相应的抗体。从临床上看,许多药物过敏反应的病理近似于血清病,一些动物实验也支持以上的看法。但是在药物过敏的病人中绝大多数找不到相应的抗体,被动转移试验很多是阴性的,与遗传的关系也 Drug allergy is a reaction caused by the use of certain drugs, whether injected, oral or direct contact may occur. It is different from the drug side effects and poisoning, it has nothing to do with the pharmacological effects of the drug, it is often unpredictable. In recent years, the incidence of allergic reactions to drugs continues to increase, understanding and correct handling of this issue is very important. Drug allergic reaction mechanism, generally considered to be based on the antigen and antibody binding occurred allergy, some people call it drug allergy. At this point, the drug is often considered a hapten, into the body after the drug or its metabolites and blood or tissue in a protein, stimulate the body to produce the corresponding antibodies. Clinically, many of the drug allergic reaction pathology is similar to serum disease, some animal experiments also support the above view. However, the vast majority of patients with drug allergies can not find the corresponding antibodies, passive transfer test is a lot of negative, and genetic relationship