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结核病的治疗,在三十年代以前主要依靠疗养,以提高机体的抵抗力,促使病灶愈合,其疗效不过30％。至四十年代加用了萎陷疗法和外科手术切除,其疗效亦仅达到40％左右,而死亡率仍然很高,且不能阻止病情发展,致使长期排菌和扩大传染源。1944年发现链霉素(SM)以后,其它抗结核化学药物如对氨水杨酸(PAS)、氨硫脲(TB_1)、异菸肼(INH)等亦相继问世,于是开创了结核病的化疗时代。合理的化疗可使疗效提高到95％以上,甚至100％。这是继卡介
The treatment of tuberculosis mainly relied on convalescence before the thirties in order to improve the body’s resistance and promote the healing of the lesion, but its efficacy is only 30%. To the forties with the addition of traumatic collapse and surgical resection, the curative effect was only 40% or so, while the mortality rate is still high, and can not stop the progression of the disease, resulting in long-term discharge of bacteria and to expand the source of infection. After the discovery of streptomycin (SM) in 1944, other anti-TB chemotherapeutics, such as pAS, TB1 and INH, also came out in succession, thus creating an era of chemotherapy for tuberculosis . Reasonable chemotherapy can improve the efficacy of more than 95%, or even 100%. This is the second card