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应用免疫组化双标记方法定位检测35例胃癌标本p53与C－erbB－2癌基因蛋白。发现p53与P185在胃癌组织中表达分别定位于不同的细胞，仅有单个细胞同时表达2种癌基因蛋白。本文并对它们在胃癌病理变化中的意义进行了初步探讨。
Immunohistochemical double-labeling method was used to locate and detect p53 and C-erbB-2 oncogene proteins in 35 gastric cancer specimens. It was found that the expression of p53 and P185 in gastric cancer tissues were located in different cells, and only a single cell expressed two oncoproteins simultaneously. This article discusses the significance of their significance in the pathological changes of gastric cancer.