论文部分内容阅读
目的:报告16例颅内结核瘤患者的临床、影像学表现及抗结核治疗的结果。设计:本文共纳入苏丹Khartoun市全国神经系统疾病中心连续观察的16例脑结核瘤患者。诊断则依据其临床、头颅影像学特征及对抗结核治疗有效等方面。本组中共有7例具有脑组织或脑外组织的病理组织学资料。结果与结论:本组病例最常见的临床表现是头痛(100%)、全身性抽搐(68.7%)及偏瘫(56.2%)。头颅横断面电子计算机体层摄影(CT)/核磁共振成像(MRI)显示单个或多个明显增强的病变及病灶周围水肿。经抗结核治疗后,多数存活患者(13/15)病变完全吸收。病变部分吸收与就诊延迟、颅内多个大病灶及晚期粟粒性结核病有关。我们主张对颅内结核瘤,即使是拟诊病例,应早期经验性试用抗结核治疗,尤其在结核病高发地区。
Objective: To report the clinical and imaging findings of 16 patients with intracranial tuberculoma and the results of anti-TB treatment. Design: This article includes 16 consecutive patients with brain tuberculosis who were consecutively observed by the National Center of Neurological Disorders in Khartoun, Sudan. Diagnosis is based on its clinical, craniographic features and effective treatment of tuberculosis and so on. A total of seven patients in this group have histopathological data of brain tissue or brain tissue. RESULTS AND CONCLUSION: The most common clinical manifestations of this group were headache (100%), generalized convulsions (68.7%) and hemiparesis (56.2%). Head cross-sectional computed tomography (CT) / magnetic resonance imaging (MRI) showed one or more significantly enhanced lesions and edema around the lesion. After anti-TB treatment, most of the survivors (13/15) completely absorbed the lesions. Part of the absorption of lesions and treatment delays, multiple intracranial lesions and advanced miliary tuberculosis. We advocate the trial of anti-TB therapy for early-stage empirical trials of intracranial tuberculoma, especially in cases of suspected tuberculosis, especially in areas with a high prevalence of TB.