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我国药剂学的研究工作最近五年来逐步有了开展,尤以1962年以后发展較快。茲分項簡述如下。一、制剂的稳定性近年来不少药剂工作者对于一些易氧化、变色、霉敗的制剂及其稳定化进行了研究。例如复方雷瑣辛酒精溶液中含有水楊酸雷瑣辛、石炭酸等药物,貯存时易氧化变紅色,为防止氧化变色,曾研究各种稳定剂的抗氧效果,所用五种稳定剂中,以混合稳定剂(即0.05 M依地酸钠0.5%,硫代硫酸鈉0.1%,焦亚硫酸鈉0.1%)及0.05 M依地酸鈉0.5%效果較好,經146天仅有微黄色;0.1%亚硫酸氢鈉、0.1%焦亚硫酸鈉、0.1%硫代硫酸鈉均較差,制剂至47
The research work of pharmacy in our country has gradually been carried out in the recent five years, especially after 1962. The breakdown is as follows. First, the stability of the preparation In recent years, many pharmaceutical workers for some of the easy oxidation, discoloration, mold and failure of formulations and their stability were studied. For example, the compound Regoluxin alcohol solution contains salicylic acid threoxocin, carbolic acid and other drugs, when stored easily oxidized red, in order to prevent oxidation discoloration, have studied the antioxidant effect of various stabilizers, the five stabilizers used, The mixed stabilizer (ie 0.05 M sodium edetate 0.5%, sodium thiosulfate 0.1%, sodium metabisulfite 0.1%) and 0.05 M sodium edetate 0.5% better, only yellowish after 146 days; 0.1% sodium bisulfite, 0.1% sodium metabisulfite, 0.1% sodium thiosulfate are poor, the preparation to 47