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目的:研究老年非小细胞肺癌患者围手术期证型变化,并探讨其防治策略。方法:共收集患者77例,分别于术前1天、术后1周、术后2周、术后1个月进行辨证,总结证候类型变化规律。结果:77例患者在4个时点共出现20个中医证型,主要以气虚血瘀、气虚血瘀+其他要素、血瘀+其他要素3种形式为主。术后气虚血瘀+其他要素、血瘀+其他要素的例数均比术前例数逐渐增多,术后2周起差异具有统计学意义(P<0.05)。在证型虚实方面,实证和虚实夹杂证较多,单纯虚证一直处于较少水平。结论:血瘀合并其他要素是老年非小细胞肺癌患者外科切除术后最主要的证型。
Objective: To study the changes of perioperative syndromes in elderly patients with non-small cell lung cancer (NSCLC) and to explore the strategies of prevention and treatment. Methods: A total of 77 patients were collected, one day before surgery, one week after surgery, two weeks after surgery, and one month after operation. The syndrome types were summarized. Results: Totally 20 Chinese medicine syndromes were found in 77 patients at 4 time points. The main forms were qi deficiency and blood stasis, Qi deficiency and blood stasis + other factors, blood stasis + other factors. After operation, the number of cases of qi deficiency and blood stasis + other factors, blood stasis + other factors increased gradually compared with the preoperative number, and the difference was statistically significant after 2 weeks (P <0.05). In the syndromes of the actual situation, there are more evidences of actuality and actuality, purely deficiency has been at a relatively low level. Conclusion: Blood stasis combined with other factors is the most important syndrome after surgical resection in elderly patients with non-small cell lung cancer.