对于恶性肿瘤的侵袭和转移这一复杂过程的基因调节机制、基因诊断和基因治疗策略,目前已成为癌细胞研究领域的关键问题,1988年由Ｓｔｅｅｇ等[1]首先发现的ｎｍ23基因,被认为是一种重要的抑癌基因[1～21],故倍受人们的关注和重视。人们对肺癌、乳腺癌、肾癌等作了许多研究和报 Gene regulation mechanisms, gene diagnosis, and gene therapy strategies for the complex process of invasion and metastasis of malignant tumors have now become key issues in the field of cancer cell research. The nm23 gene first discovered by Steeg et al. [1] in 1988 was considered Is an important tumor suppressor gene [1 ~ 21], so much attention and attention. Many studies and reports have been made on lung cancer, breast cancer, and kidney cancer.