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目的：了解急性脑梗死患者血清白细胞介素（ＩＬ－８）改变的临床意义。方法：来用开心酶联免疫吸附法（ＥＬＩＳＡ）规定４６例急性脑梗死患者和３０名健康对照者的血清ＩＬ－８浓度。结果：急性脑梗死患者急性期血清ＩＬ－８水平显著高于正常对照组（Ｐ＜０．０１）。不同部位的脑梗死患者血清ＩＬ－８含量比较：脑基底节区与非基底节区比较无明显性差异（Ｐ＞０．０５），但两组均明显高于正常对照（均为，Ｐ＜０．０１）。结论：急性脑梗死患者急性期血清ＩＬ－８水平明显升高，提示ＩＬ－８可能参与了急性脑梗死的发病过程。
Objective: To investigate the clinical significance of serum interleukin (IL-8) in patients with acute cerebral infarction. METHODS: Serum IL-8 levels were determined in 46 patients with acute cerebral infarction and 30 healthy controls by means of a haptic enzyme-linked immunosorbent assay (ELISA). Results: The level of IL-8 in acute phase of acute cerebral infarction was significantly higher than that of normal control group (P <0.01). Serum IL-8 levels in patients with cerebral infarction at different sites showed no significant difference between basal ganglia and non-basal ganglia (P> 0.05), but both groups were significantly higher than the normal control (all P < 0.01). Conclusion: Serum levels of IL-8 in patients with acute cerebral infarction are significantly increased, suggesting that IL-8 may be involved in the pathogenesis of acute cerebral infarction.