发现一类新的来源于C3H/He系的自发性突变小鼠,带有第11对常染色体的隐性突变基因。该基因型的纯系动物能引起旋转、摇头、多动和耳聋等症状。运用短声和短纯音诱发的听性脑干反应分别对生后11、17、20、35、40、89和168天的杂交突变小鼠以及生后11、20、35、40和117天的纯系突变小鼠进行听力测试。运用扫描和透射电镜分别对生后10天至18个月龄的纯系突变小鼠和生后8天 A new class of spontaneous mutant mice derived from the C3H / He line was found, with a recessive mutation of the 11th autosomal gene. The genotype of pure-line animals can cause rotation, shaking his head, hyperactivity and deafness and other symptoms. The auditory brainstem response induced by short syllables and short syllables were detected in 11, 17, 20, 35, 40, 89 and 168 days after birth and at 11, 20, 35, 40 and 117 days Pure line mutant mice for hearing test. Using scanning and transmission electron microscopy of postnatal 10 days to 18 months of pure line mutant mice and 8 days after birth