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原发性食管小细胞癌(primary esophageal small cell of carcinoma,PESC)是常见的肺外小细胞癌,临床表现与其他类型食管癌相似,但生物学行为、组织来源及治疗方法等不同于食管鳞癌、腺癌,反而与小细胞癌相似,具有恶性程度高、早期发生转移、预后差,长期生存率低等特点[1]。虽然PESC比较少见,但近年来发病率有上升趋势。本文从PESC的流行病学、病理学、治疗模式、预后等方面作一综述。
Primary esophageal small cell carcinoma (PESC) is a common extrapulmonary small cell carcinoma and its clinical manifestations are similar to those of other types of esophageal cancer. However, biological behavior, source of tissue, and treatment methods are different from esophageal squamous cell carcinoma Cancer, adenocarcinoma, on the contrary with small cell carcinoma is similar, with a high degree of malignancy, early metastasis, poor prognosis, low long-term survival characteristics [1]. Although PESC is relatively rare, the incidence has been on the rise in recent years. This article reviews the epidemiology, pathology, treatment patterns and prognosis of PESC.