论文部分内容阅读
５０例胃癌α１－抗胰蛋白酶（ＡＡＴ）和α１－抗胰糜蛋白酶（ＡＡＣＴ）免疫组化阳性分别为２６例（５２％）和２７例（５４％），６０例肠癌ＡＡＴ和ＡＡＣＴ免疫组化阳性分别为３２例（５３．３％）和３０例（５０％）；ＡＡＴ和ＡＡＣＴ阳性与阴性的胃肠癌比较，前者多分化好、组织学分级多为Ⅰ级或Ⅱ级、癌细胞多侵袭至浅肌层、区域淋巴结转移率低。这些结果提示ＡＡＴ和ＡＡＣＴ阳性胃肠道癌预后较好，ＡＡＴ和ＡＡＣＴ可能是反映胃肠道癌预后的重要生物学标记物。
The immunohistochemical positive rates of α1-antitrypsin (AAT) and α1-antitrypsin (AACT) in gastric cancer were 26 cases (52%) and 27 cases (54%) respectively, and 60 cases of AAT and AACT of colon cancer were immunized. The positive rates were 32 cases (53.3%) and 30 cases (50%), respectively; the AAT and AACT positive and negative gastrointestinal cancers were more well-differentiated, their histological grades were mostly grade I or grade II, and cancer cells Invasive to the superficial muscular layer, the lymph node metastasis rate is low. These results suggest that AAT and AACT positive gastrointestinal cancers have a better prognosis, and AAT and AACT may be important biomarkers reflecting the prognosis of gastrointestinal cancer.