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溃疡性结肠炎(简称溃结)和克隆氏病的治疗仍处在经验阶段。近年日益重视营养支持。轻病者被鼓励进正常饮食;病情影响进食者可经口或肠道外补充维生素、矿物质或低纤维和浓缩的要素饮食;完全不能进食者需给以静脉营养。过去曾希望全肠道外营养能治愈炎症性肠病,但未能实现,使疾病得以长期缓解者极少。近10年来,溃结的内科治疗仍以水杨酸偶氮磺胺吡定(SASP)为主。急性期剂量一般不超过4g/d,维持量2g/d。大剂量引起的副作用可通过逐渐增量或采用肠溶胶囊给药控制。一般变态反态性副作用的80%可用脱敏法消除。如病人耐受SASP使病情得以缓解,则长期维持用药(2~4g/D),常可防止溃结复发。SASP
Ulcerative colitis (referred to as ulceration) and Crohn’s disease treatment is still in the empirical stage. In recent years, increasing emphasis on nutrition support. Patients with mild illness are encouraged to enter the normal diet; the condition affects the diet may be oral or parenteral vitamins, minerals or low-fiber and concentrated elements of the diet; completely inaccessible who need to be given intravenous nutrition. In the past had hoped that total parenteral nutrition can cure inflammatory bowel disease, but failed to achieve, make the disease can be long-term remission were minimal. In the past 10 years, the medical treatment of ulceration is still salicylate sulfasalazine (SASP). Acute dose usually does not exceed 4g / d, maintenance dose 2g / d. Side effects caused by high doses can be controlled incrementally or by enteric-coated capsules. 80% of the general metamorphic side effects can be eliminated by desensitization. If patients tolerate SASP to ease the condition, the long-term maintenance medication (2 ~ 4g / D), often prevent ulcer recurrence. SASP