视网膜母细胞瘤(Retinoblastoma)是一种多见于儿童期的恶性肿瘤,常引致患儿的死亡和失明,约占儿童肿瘤死亡率的1％和盲童的5％。此瘤具有发病早,双侧性多和家族性集聚的特点,是久已为人们所注意的典型遗传性肿瘤。近年来已能利用染色体显带技术,准确地识别每一条染色体,为研究视网膜母细胞瘤和遗传物质改变的关系提供了新方法。 Retinoblastoma is a childhood malignant tumor that often leads to death and blindness in children, accounting for about 1% of childhood cancer deaths and 5% of blind children. This tumor has the characteristics of early onset, bilateral and multi-familial agglutination, and is a typical hereditary tumor that has long been noticed by people. In recent years, we have been able to use the chromosome banding technology to accurately identify each chromosome, which provides a new method for studying the relationship between retinoblastoma and genetic material changes.