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作者总结了经组织学证实的60例Wegener氏肉芽肿病例,其中27例(45%)发现耳部已被侵犯,表现为活动的或静止的中耳病变,绝大部份呈持续的或反复发作的浆液性中耳炎。 Wegener氏肉芽肿病患者耳部受累可以是原发性,亦可为继发性,其所并发的浆液性中耳炎是因鼻腔感染导致咽鼓管功能障碍引起,一般的抗炎、脱敏治疗无效,多需长期或反复行鼓室插管,只有待鼻部症状得到控制、咽鼓管功能恢复后耳部症状才能好转,它还能遗留粘连性中耳炎和鼓室硬化,但因咽鼓管不良不宜手术治疗。少数浆液性中耳炎可继发感染成化脓性中耳炎,细菌培养多为金黄色葡萄球菌和绿脓杆菌。作者们认为如药物不能控制感染需行乳突根治术治疗,
The authors summarized 60 cases of Wegener’s granulomatosis confirmed histologically, 27 of which (45%) found that the ear had been invaded and showed active or silent middle ear lesions, most of which were persistent or repeated Serous otitis media. Wegener’s granulomatosis patients with ear involvement may be primary, but also secondary, its concurrent serous otitis media is caused by nasal infection caused by eustachian tube dysfunction, the general anti-inflammatory, desensitization therapy is invalid , The need for long-term or repeated tympanic intubation, nasal symptoms to be controlled until the eustachian tube function to recover after the ear symptoms can be improved, it can still leave the adhesive otitis media and tympanic sclerosis, but due to poor eustachian tube surgery treatment. A small number of serous otitis media can be secondary infection into suppurative otitis media, bacterial culture mostly Staphylococcus aureus and Pseudomonas aeruginosa. The authors believe that if the drug can not control the infection need radical mastoidectomy,