分子生物学的飞速发展对闸明癌的发生以及增殖机理起到极大作用。目前已发现的癌基因有50多种。癌基因的活化可导致增殖因子或受体产生过剩,进而通过自分泌系统影响癌细胞的增殖。本文着重对脑肿瘤特别是与神经胶质瘤有关的增殖因子和受体的分子生物学特性及临床应用进行阐述。 The rapid development of molecular biology has played an important role in the occurrence of cancer and the mechanism of proliferation. More than 50 oncogenes have been discovered. Activation of oncogenes can lead to excess production of proliferative factors or receptors, which in turn affect cancer cell proliferation through the autocrine system. This article focuses on the molecular biological characteristics and clinical applications of brain tumors, particularly those associated with gliomas.