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目的:分析需手术治疗的初诊食管癌患者围手术期间,除了术中出血之外,其他与输注异体红细胞相关的影响因素。方法:回顾性收集178例经手术治疗的食管癌患者的临床资料及输注异体红细胞情况,并对输血相关因素进行单因素和多因素Logistic回归分析。结果:178例食管癌患者中有23例输注1U及以上悬浮红细胞,输血率12.9%。单因素Logistic回归分析结果提示年龄、术前Hb浓度、术前白蛋白浓度、肿瘤TNM分期,是患者围手术期是否输注异体红细胞的影响因素(P<0.05)。多因素Logistic回归分析提示性别、体重指数、白细胞数量、食管癌长度、位置、手术方式、术前肺功能情况、患者血型、凝血常规情况对成分输血无显著影响(P>0.05)。结论:年龄、术前Hb浓度、术后肿瘤TNM分期,尤其是术前低白蛋白血症,是影响患者是否需要输注红细胞的影响因素。
OBJECTIVE: To analyze the influencing factors of allogeneic erythrocytes other than intraoperative bleeding in the newly diagnosed esophageal cancer patients undergoing surgical treatment. Methods: Retrospectively collected 178 cases of esophageal cancer patients undergoing surgical treatment of clinical data and the situation of allogeneic red blood cells transfusion, and blood transfusion related factors by single factor and multivariate logistic regression analysis. Results: Of the 178 patients with esophageal cancer, 23 patients were infused with 1U or more of suspended erythrocytes and the transfusion rate was 12.9%. Logistic regression analysis showed that age, preoperative Hb concentration, preoperative albumin concentration and tumor TNM stage were the influencing factors of perioperative infiltration of allogeneic erythrocytes (P <0.05). Multivariate Logistic regression analysis showed no significant effect on blood transfusion from gender, body mass index, white blood cell count, esophageal cancer length, location, operation method, preoperative pulmonary function, blood type and coagulation status. Conclusion: Age, preoperative Hb concentration, postoperative tumor TNM staging, especially preoperative hypoalbuminemia, are the influencing factors of whether patients need to transfused erythrocytes.