用异丙肾上腺素诱发大鼠心肌坏死模型对红藤水溶性提取物红藤甲素、丙素及多糖进行比较研究。连续两天给药(每天5mg/kg)并记录EKG变化,第三天开胸取心进行病理学检查。EKG和病理学检查结果均表明,三种成分中多糖对缺血心肌的保护作用最强,丙素有微弱的保护作用,而甲素未见有统计学的显著差异。 A rat model of myocardial necrosis induced by isoproterenol was used to compare the water-soluble extracts of erythromycin, propylpropanoid and polysaccharides. Administration was continued for two consecutive days (5 mg/kg per day) and changes in EKG were recorded. On the third day, the heart was opened and the heart was examined for pathology. Both EKG and pathological examinations showed that polysaccharides in the three components had the strongest protective effect on ischemic myocardium, and propanol had a weak protective effect, while there was no statistically significant difference in the preservatives.