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目的探讨乳腺癌规范化保乳治疗的临床疗效。方法 103例原发性乳腺癌接受局部扩大切除术+前哨淋巴结活检或腋窝淋巴结清扫术治疗,手术后患侧乳房接受放射治疗。回顾性分析患者的临床和病理资料,随访监测局部复发或新发及远处转移情况。结果 103例患者保乳手术顺利,术后随访外形满意。中位随访时间49(3~112)个月,4例同侧乳腺局部复发,其中3年内局部复发1例(1.0%),3~4年局部复发3例(2.9%)。新发乳腺癌2例(1.9%),远处转移2例(1.9%),无死亡病例。结论规范化保乳手术治疗乳腺癌的临床疗效满意,可作为0期及Ⅰ~Ⅱ期乳腺癌的首选治疗方法。
Objective To investigate the clinical efficacy of standardized breast-conserving therapy for breast cancer. Methods A total of 103 cases of primary breast cancer underwent local enlargement resection plus sentinel lymph node biopsy or axillary lymph node dissection. The affected breast received radiotherapy after operation. Retrospective analysis of patients with clinical and pathological data, follow-up monitoring of local recurrence or new and distant metastasis. Results The operation of breast-conserving surgery was successful in 103 patients, and the shape of postoperative follow-up was satisfactory. The median follow-up time was 49 (3-12) months. Four cases of ipsilateral mammary gland local recurrence were found. One case (1.0%) had local recurrence in 3 years and 3 cases (2.9%) had local recurrence in 3 ~ 4 years. Two cases of new breast cancer (1.9%), distant metastasis in 2 cases (1.9%), no deaths. Conclusion The standardized breast-conserving surgery for breast cancer with satisfactory clinical efficacy can be used as 0 and Ⅰ ~ Ⅱ breast cancer treatment of choice.