拉萨地区藏药、西药对照治疗溃疡病100例的临床研究

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目的 :探讨藏药、西药治疗消化性溃疡的临床疗效。方法 :拉萨地区消化性溃疡患者 1 0 0例 ,随机分为治疗组 (藏药 )、对照组 (西药 )两组 ,每组各 50人 ;藏药组口服坐珠达西 1丸Bid ,木布玉杰 3丸Bid ,玉琼4丸Qd。西药组口服Losec 2 0mgQd ,BismuthPectin1 0 0mgTid ,抗HP加用Amoxycillin 0 5mgTid口服 2周。治疗 4周后复查胃镜及HP。结果 :治疗组球部溃疡、胃溃疡的愈合率分别为 4 8%、81 % ,对照组球部溃疡、胃溃疡的愈合率分别为 :81、3 6% ,两组比较X2 =1 6 75,差异有显著性 (P <0 0 0 1 )。其中 ,治疗组胃溃疡的疗效明显高于对照组 ,而球部溃疡的疗效则略低于对照组 ;本次研究得出治疗组、对照组溃疡的愈合率分别为 57%、61 % ,两组间总体愈合率接近 ,愈合率及愈合质量对比差异均无显著性 (P =0 1 76,P >0 0 5) ;治疗组、对照组HP清除率分别为 1 5%、69% (差异有显著性X2 =2 5 0 2 ,P <0 0 0 1 )。结论 :本地区藏、西药治疗消化性溃疡的愈合率接近 ,藏药 4周疗程的费用明显低于西药 ,这一点也适应本地区社会经济发展状况及符合民族习惯 ,因而综合评价 ,该药治疗消化性溃疡的临床疗效肯定。而藏医学作为祖国传统医学 ,藏药作为无污染、特殊生态环境下绿色环保产品 ,符合当今国际医药界的发展趋 Objective: To explore the clinical efficacy of Tibetan medicine and Western medicine in the treatment of peptic ulcer. Methods: One hundred and ten patients with peptic ulcer in Lhasa were randomly divided into two groups: treatment group (Tibetan medicine) and control group (Western medicine) Buyujie 3 pills Bid, Yu Qiong 4 pills Qd. Western medicine group oral Losec 2 0mgQd, BismuthPectin1 0mgTid, anti-HP plus Amoxycillin 0 5mgTid oral for 2 weeks. Gastroscopy and HP were reviewed after 4 weeks of treatment. Results: The healing rates of bulb ulcer and gastric ulcer in treatment group were 48% and 81%, respectively. The healing rates of bulb ulcer and gastric ulcer in control group were 81 and 36%, respectively. X2 = 1 675 , The difference was significant (P <0 0 0 1). The curative effect of gastric ulcer in the treatment group was significantly higher than that in the control group, while the efficacy of the ulcer in the ulcer was slightly lower than that in the control group. The healing rates of the ulcer in the treatment group and the control group were 57% and 61% There was no significant difference in healing rate and healing quality between the two groups (P = 0 1 76, P 0 05). The clearance rates of HP in the treatment group and control group were respectively 15% and 69% (difference There is significant X2 = 2 5 0 2, P <0 0 0 1). Conclusion: The healing rates of peptic ulcer in Tibet and western medicine in this area are similar, and the cost of 4 weeks of Tibetan medicine treatment is obviously lower than that in western medicine. This also adapts to the socio-economic development in our region and accords with ethnic customs. Therefore, the comprehensive evaluation, The clinical efficacy of peptic ulcer certainly. Tibetan medicine as traditional medicine in the motherland and Tibetan medicine as a green product in a non-polluting and special ecological environment are in line with the development trend of today’s international pharmaceutical community
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