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已知食管对酸的清除分两个阶段,一是食管的蠕动,可迅速排空90～95％食管内的酸性食团;二是咽下的唾液可中和食管腔内残余酸,作者研究的目的在于检测远段食管内滴注不同浓度的盐酸对整个唾液和腮腺液流出率的影响;确定食管内不同的酸浓度对唾液中碳酸氢盐分泌的影响;研究人体酸诱导唾液分泌的机理;检测食管滴注液渗透克分子浓度的变化对唾液分泌的影响及酸诱导的胃灼痛和唾液分泌与食管酸滴注浓度的相关性,以进一步观察食管内酸诱导的唾液分泌情况。
Esophageal acid removal is known to be divided into two phases, one is the esophageal peristalsis, can quickly emptying 90 to 95% of the esophagus within the esophagus; Second, swallow saliva can be in the esophageal cavity residual acid, the study The purpose is to detect the distal esophageal instillation of different concentrations of hydrochloric acid on the salivary and parotid effusion rate; to determine the different esophageal acid concentration on saliva bicarbonate secretion; study of human acid-induced salivary secretion mechanism The effect of esophageal instillation of esophageal instillation on the secretion of saliva and the correlation between acid-induced heartburn and salivary secretion and esophageal acid instillation were examined.