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用原子力显微镜观察了培养的人黑素细胞和鼠黑素瘤细胞Ｂ１６Ｆ１０ 细胞的树枝状突。发现两种细胞的树枝状突均有第二级分枝， 在第二级分枝主干及支干的顶端和侧缘均可见膨出的球形结构。在树枝状突的表面还可见很多均匀一致的直径３００ ～５００ｎｍ 左右的颗粒。本实验显示： 黑素细胞除通过树枝状突的顶端输送黑素颗粒外， 还可通过第二级分枝的顶端和侧缘输送； 黑素颗粒可通过胞吐将其排出； 原子力显微镜还可以观察到细胞内部的黑素小体。
Dendrites of cultured human melanocytes and murine melanoma cells B16F10 cells were observed with an atomic force microscope. It was found that the dendrites of both cells had second-level branches, and bulging spherical structures were visible on the top and lateral edges of the second-level branches and stems. In the dendritic surface can also see a lot of uniform diameter of about 300 ~ 500nm particles. This experiment shows that melanocytes can be delivered via the apices and lateral edges of the secondary branches in addition to melanosomes delivered through the apices of dendrites; melanosomes can be excreted by exocytosis; and AFM can also Melanosomes inside the cells were observed.