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目的探讨康妇消炎栓联合阿奇霉素序贯疗法对急性盆腔炎患者炎症反应的影响。方法选择2015年11月-2016年10月新昌县中医院收治的94例急性盆腔炎患者为研究对象,随机分为观察组和对照组,每组47例。对照组给予阿奇霉素序贯治疗。观察组在对照组基础上,给予康妇消炎栓治疗。对比两组细菌清除率和治疗前后血清C反应蛋白(CRP)、干扰素γ(IFN-γ)、白介素1β(IL-1β)、降钙素原(PCT)的水平。结果观察组的疗效显著优于对照组(P<0.05);观察组的细菌清除率显著高于对照组(P<0.05);两组治疗后CRP、IFN-γ、IL-1β、PCT的水平较治疗前均明显降低(P<0.05);治疗后,观察组的CRP、IFN-γ、IL-1β、PCT明显低于对照组(P<0.05)。结论康妇消炎栓联合阿奇霉素序贯能显著减轻急性盆腔炎患者的炎症反应。
Objective To investigate the effect of Kangfu anti-inflammatory suppository combined with azithromycin sequential therapy on the inflammatory response in patients with acute pelvic inflammatory disease. Methods 94 patients with acute pelvic inflammatory disease admitted from Xinchang Hospital of Traditional Chinese Medicine from November 2015 to October 2016 were selected as study subjects and randomly divided into observation group and control group, with 47 cases in each group. Control group given azithromycin sequential treatment. The observation group was given Kangfu anti-inflammatory suppository on the basis of the control group. The bacterial clearance and the levels of serum C-reactive protein (CRP), interferon gamma (IFN-γ), interleukin-1β (IL-1β) and procalcitonin (PCT) Results The efficacy of the observation group was significantly better than that of the control group (P <0.05). The bacterial clearance rate of the observation group was significantly higher than that of the control group (P <0.05). The levels of CRP, IFN-γ, IL- (P <0.05). After treatment, the levels of CRP, IFN-γ, IL-1β and PCT in the observation group were significantly lower than those in the control group (P <0.05). Conclusion Kangfu anti-inflammatory suppository combined with azithromycin sequential treatment can significantly reduce the inflammatory response in patients with acute pelvic inflammatory disease.