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氨酰心安是美国近年来用于治疗高血压的选择性β_1受体拮抗剂。氨酰心安具有心得安,美多心安及(艹佘)羟心安的药理学优点.它较(艹佘)羟心安吸收好.约为口服60％.血浆蛋白结合很少,代谢物无明显活性.半衰期6—7小时,肾功不良者可达100小时以上,故肌酐清除率降低者应减少用量.因氨酰心安系水溶性β阻滞剂,高血压病及心绞痛患者每日用药一次即有效.
Atenolol is the United States in recent years for the treatment of hypertension selective β 1 receptor antagonist. Atenolol with peace of mind, the United States more peace of mind and (艹 She) hydroxyxinan pharmacological advantages than it (艹 She) hydroxyxin and good absorption of about 60% orally. Plasma protein binding is little, the metabolites no significant activity Half-life of 6-7 hours, renal dysfunction, up to 100 hours or more, so reduce the creatinine clearance rate should reduce the amount of due to atenolol water-soluble beta blockers, hypertension and angina pectoris medication once daily effective.