目的从治疗学的角度探讨慢性盆腔疼痛综合征的可能病因及治疗选择。方法112例门诊诊断为慢性盆腔疼痛综合征的患者根据前列腺液中白细胞数量大于或小于等于10个/高倍视野,分为Ⅲa(炎症性)组和Ⅲb(非炎症性)组;两组患者接受相同的治疗,口服塞来昔布,治疗随访6周;比较两组患者治疗前后慢性前列腺炎症状评分及前列腺液中卵磷脂小体数量的变化。结果每组患者治疗前后及两组患者治疗后的症状评分和前列腺液中卵磷脂小体数量的变化均有统计学意义。结论炎症反应能导致慢性盆腔疼痛综合征;特异性环氧化酶Ⅱ抑制剂对慢性盆腔疼痛综合征有较好的疗效,其对Ⅲa型(炎症性)的疗效优于Ⅲb型(非炎症性)。 Objective To explore the possible causes and treatment options of chronic pelvic pain syndrome from the perspective of therapeutics. Methods One hundred and twelve outpatients diagnosed as chronic pelvic pain syndrome were divided into Ⅲa (inflamed) group and Ⅲb (non-inflamed) group according to the number of leukocytes in prostatic fluid greater than or equal to 10 / high magnification. Patients in both groups received The same treatment, oral celecoxib, the treatment was followed up for 6 weeks; before and after treatment of two groups of patients with chronic prostatitis symptom score and prostatic fluid lecithin number changes. Results Before and after treatment in each group and two groups of patients after treatment symptom scores and prostatic fluid lecithin number changes were statistically significant. Conclusion Inflammatory reaction can lead to chronic pelvic pain syndrome. Specific cyclooxygenase Ⅱ inhibitor has a good curative effect on chronic pelvic pain syndrome. Its effect on type Ⅲa (inflammatory) is better than that of type Ⅲb (non-inflammatory ).