氟哌酸是一种新型的口服喹诺酮类抗生素。作者用该药预防恶性血液病患者因化疗所致严重粒细胞减少(<10×10_(?)~(?)/L)时的细菌性感染,并与安慰剂、万古-多粘菌素、TMP/SMX组进行对比,效果佳。方法:患者随机分组对照观察,各组药物均在化疗开始时就用。剂量:氟哌酸400mg,万古霉素500mg,多粘菌素100mg,TMP 160mg,SMX 800mg, Norfloxacin is a novel oral quinolone antibiotic. The authors used the drug to prevent bacterial infections in patients with hematologic malignancies due to chemotherapy-induced severe neutropenia (<10 × 10 ~ (?)? / L), compared with placebo, vancomycin-polymyxin, TMP / SMX group for comparison, good effect. Methods: The patients were randomly divided into control group. All the drugs were used at the beginning of chemotherapy. Dosage: Norfloxacin 400 mg, vancomycin 500 mg, polymyxin 100 mg, TMP 160 mg, SMX 800 mg,