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A novel experimental procedure was proposed to investigate the phase behavior of a solvent mixture(SM)(64 mol％ CH4,8 mol％ C02,and 28 mol％ C3H8)with heavy oil.Then,a theoretical methodology was employed to estimate the phase behav-ior of the heavy oil-solvent mixture(HO-SM)systems with various mole fractions of SM.The experimental results show that as the mole fraction of SM increases,the saturation pressures and swelling factors of the HO-SM systems considerably increase,and the viscosities and densities of the HO-SM systems decrease.The heavy oil is upgraded in situ via asphaltene precipitation and SM dissolution.Therefore,the solvent-enriched oil phase at the top layer of reservoirs can easily be pro-duced from the reservoir.The aforementioned results indicate that the SM has promising application potential for enhanced heavy oil recovery via solvent-based processes.The theoretical methodology can accurately predict the saturation pressures,swelling factors,and densities of HO-SM systems with various mole fractions of SM,with average error percentages of 1.77％ for saturation pressures,0.07％ for swelling factors,and 0.07％ for densities.