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精神科临床中,使用抗精神病药经常遇到静坐不能的副反应。其特征为不适、坐立不安、心神不定。对此类药源性静坐不能,传统的治疗方法是使用抗巴金森氏病药,苯二氮莗类和金刚胺等。但临床治疗效果不理想,往往因此影响精神病的治疗。新近国外研究发现,β-受体阻滞剂心得安治疗此类静坐不能,疗效可靠且安全。我院收集了15例抗精神病药所致静坐不能患者,初步探讨了心得安对他们的疗效。现报道如下。方法15例患者均系我院住院病人,男14例,女1例,年龄为23～46岁,平均年龄33.7岁。诊断均为精神分裂症(按DSM—Ⅲ标准),并均在接受抗精神病药治疗过程中出现静坐不能。所用抗精神病
Psychiatric clinics, the use of antipsychotic medications often encounter side effects can not be. It is characterized by discomfort, restlessness, uncertainty. For such drug-induced seizures can not, the traditional treatment is the use of anti-Parkinson’s disease drugs, benzodiazepines and amantadine and so on. However, the clinical treatment effect is not ideal, often thus affecting the treatment of mental illness. Recent studies abroad found that beta-blockers are safe treatment of such sit-in, reliable and safe. Our hospital collected 15 cases of patients with meditation due to antipsychotics, initially discussed the effect of propranolol on them. Report as follows now. Methods 15 patients were hospitalized in our hospital, 14 males and 1 female, aged from 23 to 46 years, with an average age of 33.7 years. All diagnoses were schizophrenia (according to the DSM-III standard) and were not able to meditate during antipsychotic treatment. Anti-psychosis used