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自1970～1983年间共诊治鼻腔、鼻窦乳头状瘤267例,其中内翻性者260例,外生性者7例;男与女之比为3:1;40～59岁为发病高峰年龄,占62.7％。复发130例(48.1％),恶变25例(9.4％)。死亡7例(2.6％)。肿瘤主要发生于鼻腔侧壁,易侵犯上颌窦、筛窦。临床症状以单侧性鼻塞、鼻分泌物增多为主。内翻性者以柱状上皮及柱状、移行、鳞状上皮的混合性上皮为主,复发率较外生性者为高,伴有外生乳头形成者恶变率升高。治疗以手术为主,病变范围越广,效果越差。肿瘤复发与手术不彻底有关,但与组织像之间无明显关系。
From 1970 to 1983, a total of 267 cases of nasal and sinusoidal papillomas were diagnosed and treated, of which 260 cases were inverted and 7 cases were exogenous; the ratio of male to female was 3:1; the peak age of onset was 40 to 59 years of age. 62.7%. 130 cases (48.1%) relapsed and 25 cases (9.4%) changed malignantly. Seven patients died (2.6%). The tumor mainly occurs in the side wall of the nasal cavity, and is easily invaded by maxillary sinus and ethmoid sinus. Clinical symptoms include unilateral nasal congestion and increased nasal secretions. Inverted persons were mainly composed of columnar epithelium and mixed epithelium of columnar, transitional, and squamous epithelium. The recurrence rate was higher than that of exogenous individuals, and the malignant transformation rate of exogenous nipple formation was increased. Treatment is based on surgery, and the wider the lesion, the worse the effect. Tumor recurrence is not related to surgery, but there is no obvious relationship with the tissue image.